Key result
Having a mental disorder significantly worsened health-related quality of life by 71.2% (exp(β)=0.288) compared to propensity-matched individuals without mental disorders.
Why the study?
Does the presence of mental disorders reduce health-related quality of life in the Korean population?
Case-Control (n=354)
Does the presence of mental disorders reduce health-related quality of life in the Korean population?
Mental disorders are associated with a significant reduction in health-related quality of life in the Korean population.
Mental disorders were associated with substantially lower HRQoL in Korea; leaves open whether targeted interventions improve outcomes.
Background: Despite the importance of the health-related quality of life (HRQoL) in mental health, research into HRQoL among people with mental disorders remains limited in Korea. Aims: To quantify the impact of mental disorders on HRQoL in the Korean context. Methods: Propensity score matching was used to establish a case-control database. A total of 177 people with mental disorders (38.4% with schizophrenia, 21.5% with bipolar affective disorder, 20.3% with recurrent depressive disorder and 19.8% with other mental conditions) were surveyed and matched with an equal number of individuals without mental disorders from the Korean National Health and Nutrition Examination Survey. HRQoL was measured using the EuroQol-5 Dimension (EQ-5D) scale. Multivariate beta regression analysis was performed to assess the impact of mental disorders on HRQoL. Results: Individuals with mental disorders had significantly lower EQ-5D index scores (0.854, SD 0.144) than those without mental disorders (0.972, SD 0.067) (p<0.0001). According to the results of the multivariate beta regression analysis, having a mental disorder was found to significantly worsen HRQoL by 71.2%(exp(-1.244)=0.288, p<0.0001). Additionally, self-rated health was found to significantly improve HRQoL in people with mental disorders. Rating one's health as 'good' was associated with a 95.1% (β=0.668, p=0.0029) increase in EQ-5D score compared to rating it as 'poor'. Conclusion: The presence of mental disorders was significantly associated with lower HRQoL. Further in-depth studies are needed to explore HRQoL among individuals with mental disorders from a variety of perspectives, particularly within the Korean context.
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Lee et al. (2025) conducted a case-control in Mental disorders (n=354). Mental disorders vs. No mental disorders was evaluated on Health-related quality of life (EQ-5D index score) (exp(β) 0.288, p=<0.0001). Having a mental disorder significantly worsened health-related quality of life by 71.2% (exp(β)=0.288) compared to propensity-matched individuals without mental disorders.
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