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A historical review of mid-palatal suture maturation (MPSM) is presented to observe the mechanism underlying the evolution of the maturation index set forth for MPSM over time.This review was prepared as a part of a clinical study that investigated the possibility of employing cervical vertebrae maturation (CVM) as a predictor for informing clinicians regarding the maturation status of mid-palatal sutures (MPS).Scientific literature from major indexed databases (Scopus, Medline, PubMed, and Biosis) was included to isolate relevant related papers dating back to the earliest times.The review presents the various methods used to predict various stages of MPSM, with hand wrist radiographs (HWR) and CVM being the most frequently used.For each method, the relevant stages observed were related to the stage of MPSM in both genders, and thus, the necessary intervention (nonsurgical or surgical) for rapid maxillary expansion in constricted maxillary arches can be determined.
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Mattoo et al. (2025) studied this question.
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