Key result
The kink turn is a widespread structural motif in duplex RNA that functions as a key architectural element in riboswitches to help generate the ligand binding pocket.
The kink turn is a widespread structural motif in RNA that mediates tertiary interactions and protein binding, serving as a key architectural element in riboswitches.
K-turns may enable riboswitch engineering; leaves open therapeutic translation to cardiovascular gene regulation.
The kink turn is a widespread structure motif that introduces a tight bend into the axis of duplex RNA. This generally functions to mediate tertiary interactions, and to serve as a specific protein binding site. K-turns or closely related structures are found in at least seven different riboswitch structures, where they function as key architectural elements that help generate the ligand binding pocket. This article is part of a Special Issue entitled: Riboswitches.
No takes yet. Share an insight, caveat, or question.
David M.J. Lilley (2014) reported a review. The kink turn is a widespread structural motif in duplex RNA that functions as a key architectural element in riboswitches to help generate the ligand binding pocket.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: