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April 6, 2022Therapeutic Drug Monitoring

Towards Precision Dosing of Clozapine in Schizophrenia: External Evaluation of Population Pharmacokinetic Models and Bayesian Forecasting

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Authors

ALAurélie LereclusInsermTKThéo KorchiaAix-Marseille UniversitéCRCamille RiffAstraZeneca (Sweden)

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Lereclus et al. (2022) studied this question.

synapsesocial.com/papers/6ab4c569fcd54fdadea72828https://doi.org/10.1097/ftd.0000000000000987
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Serum Clozapine Levels: A Review of Their Clinical Utility2003 · 88 citations
  2. 2Influence of dose, gender, and cigarette smoking on clozapine plasma concentrations2018 · 67 citations
  3. 3From Therapeutic Drug Monitoring to Model‐Informed Precision Dosing for Antibiotics2021 · 266 citations
  4. 4Population pharmacokinetics of clozapine evaluated with the nonparametric maximum likelihood method1997 · 66 citations
  5. 5Towards precision dosing of vancomycin: a systematic evaluation of pharmacometric models for Bayesian forecasting2019 · 131 citations