All articles of this category A versatile chiral building block (7a R )-5,6-dihydro-7a-methyl-1 H -indene-2,7(4 H ,7a H ) -dione ( 4 ) was firstly enantiomerically synthesized from the microbial transformation ketol product 6 in 61.3% overall yield and over 96% ee. asymmetric synthesis - microbial reduction - ketols - bicyclic compounds - Wieland-Miescher ketone analog
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Wei et al. (2000) studied this question.