Key result
Neonatal intrapericardial rhabdomyosarcoma proves fatal despite surgery and chemotherapy due to septic shock.
Why the study?
Malignant cardiac tumors in neonates are rare, with intrapericardial rhabdomyosarcoma being extremely uncommon and scarcely reported.
Case Report (n=1)
This case report highlights an extremely rare presentation of intrapericardial rhabdomyosarcoma in a newborn, adding to the very limited literature on this condition.
Adds second neonatal intrapericardial RMS case; extends sparse literature but leaves management and prognosis questions open.
Cardiac tumors are uncommon in neonates and most of them are histologically benign. The most common cardiac tumor in neonates and infants is rhabdomyoma. Malignant cardiac tumors are considerably rarer, and rhabdomyosarcoma (RMS) is the leading malignancy. To our knowledge, only one case of intrapericardial RMS was reported in the literature, in a seven-month-old baby. Here we present another newborn baby with intrapericardial RMS.
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Tutak et al. (2008) conducted a case report in Intrapericardial rhabdomyosarcoma (n=1). Surgery and chemotherapy (vincristine, actinomycin-D, cyclophosphamide) was evaluated on Clinical outcome. A 21-day-old female newborn with intrapericardial rhabdomyosarcoma died on the 34th day of admission due to septic shock despite surgical and chemotherapy interventions.
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