Polysaccharide fractions of the leaves of a number of Aloe species significantly reduced blood sugar level in mice. Activity-directed fractionation of the polysaccharide fraction from Aloe arborescens Mill. var. natalensis (Wood, et Ev.) Bgr. leaves yielded two glycans, arborans A and B, which elicited marked hypoglycemic effects in normal and alloxan-induced hyperglycemic mice.
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Hikino et al. (1986) studied this question.
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