Key result
Colour M-mode Vp and EDS correlate with traditional diastolic grades but discriminate poorly across severity.
Why the study?
The clinical value of Vp and EDS as parameters to assess left ventricular diastolic function compared with traditional Doppler evaluation was unclear.
Do Vp and EDS add clinical value to traditional Doppler evaluation for assessing left ventricular diastolic function in consecutive patients?
Cross-Sectional (n=65)
Do Vp and EDS add clinical value to traditional Doppler evaluation for assessing left ventricular diastolic function in consecutive patients?
Vp and EDS do not add significant clinical value to traditional Doppler evaluation for assessing left ventricular diastolic function due to poor discrimination between normal and highly abnormal states.
AIMS: To study the clinical value of the colour-M-mode slope of the early diastolic left ventricular filling phase (Vp) and the early diastolic downward M-mode slope of the left atrioventricular plane displacement (EDS), compared with diastolic function assessed by traditional Doppler evaluation. METHODS AND RESULTS: In 65 consecutive patients EDS and Vp were compared with a four-degree traditional diastolic function classification, based on pulsed Doppler assessment of the early to atrial transmitral flow ratio (E/A), the E-wave deceleration time (Edt), and the systolic to diastolic (S/D) pulmonary venous inflow ratio. Vp (P=0.006) and EDS (P=0.045) were related to traditional diastolic function (Kruskal--Wallis analysis). EDS showed a trend brake between the moderate and severe diastolic dysfunction groups by traditional Doppler evaluation. Vp and EDS correlated weakly in simple linear regression analysis (r=0.33). Vp and EDS discriminated poorly between normal and highly abnormal diastolic function. CONCLUSIONS: Vp and EDS were significantly related to diastolic function by traditional Doppler evaluation. They were, however, not useful as single parameters of left ventricular diastolic function due to a small difference between normal and highly abnormal values, allowing for little between-measurement variability. Consequently, these methods for the evaluation of left ventricular diastolic function do not add significantly to traditional Doppler evaluation.
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Reidar Winter (2001) conducted a cross-sectional in Diastolic dysfunction (n=65). Colour-M-mode Vp and EDS vs. Traditional Doppler evaluation was evaluated on Relationship to traditional diastolic function classification (p=0.006 (Vp), 0.045 (EDS)). Colour-M-mode Vp and EDS were significantly related to traditional Doppler diastolic function (P=0.006 and P=0.045) but discriminated poorly between normal and highly abnormal function.
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