Transfusion-related acute lung injury (TRALI) has emerged as one of the leading causes of transfusion-related morbidity and mortality and is undoubtedly under diagnosed. It is a serious pulmonary syndrome that can lead to death if not recognised and treated promptly. The diagnosis of TRALI is based primarily upon clinical signs and symptoms and is, in part, a diagnosis of exclusion.
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Aravinthan et al. (2009) studied this question.
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