A template-directed synthesis of oligonucleotide in the presence of polystyrene-supported neutral oligonucleotide derivative was studied. The oligonucleotide which has the sequence of the complementary base with the template, the neutral oligonucleotide derivative, yielded with a considerable amount, when the template with degree of oligomerization of 4 was used.
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Shimidzu et al. (1976) studied this question.
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