Key result
Obesity potentially impacts prostate cancer through a complex relationship involving both biological and non-biological mechanisms.
Why the study?
How does obesity impact prostate cancer?
How does obesity impact prostate cancer?
This review discusses the complex biological and non-biological mechanisms by which obesity may impact prostate cancer.
Complex obesity-prostate cancer link warrants caution in risk stratification; leaves open need for prospective studies before practice change.
Prostate cancer is the most common non-cutaneous malignancy diagnosed in US men. With the increasing prevalence of obesity, it is of interest how this condition impacts prostate cancer. However, only recently has the relationship between obesity and prostate cancer been earnestly studied by investigators. Indeed, the relationship between obesity and prostate cancer appears to be complex one. Therefore, we sought to review the most recent and relevant epidemiological data discussing the link between prostate cancer and obesity. In this review, we will discuss both "biological" and "non-biological" means by which obesity may potentially impact prostate cancer.
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Stephen J. Freedland (2010) conducted a review in Prostate cancer. Obesity was evaluated. Obesity potentially impacts prostate cancer through a complex relationship involving both biological and non-biological mechanisms.
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