Elaboration of Bicarbonate Ion in Intraocular Fluids

The vitreous humor is considered to be an important reservoir in the diffusional exchange of substances with the aqueous humor of the posterior chamber. Indeed, Christiansson and Palm1and Kinsey and Palm,2as well as Friedenwald and Becker,3have shown that failure to take into account the dynamic properties of the chemical components of the vitreous humor in diffusional exchange with those in the aqueous humor leads to inaccurate estimates of the rate of flow of aqueous humor. Furthermore, determination of the distribution of substances in the different sections of the vitreous humor gives some idea as to the routes by which they enter. Thus, Duke-Elder and Davson,4by a modification of the technique employed by Adler,5concluded from the uniform distribution of glucose in the vitreous humor under normal conditions and when the blood sugar level was high that glucose diffuses into the vitreous