Key result
Early transcatheter aortic-valve replacement (TAVR) was reported to be superior to clinical surveillance in reducing death, stroke, or unplanned cardiovascular hospitalization.
Why the study?
Does early transcatheter aortic-valve replacement (TAVR) reduce the composite of death, stroke, or unplanned hospitalization for cardiovascular causes in patients with asymptomatic severe aortic stenosis compared to clinical surveillance?
Does early transcatheter aortic-valve replacement (TAVR) reduce the composite of death, stroke, or unplanned hospitalization for cardiovascular causes in patients with asymptomatic severe aortic stenosis compared to clinical surveillance?
Early TAVR is reported to be superior to clinical surveillance in asymptomatic severe aortic stenosis, expanding its therapeutic role beyond operative-risk classification.
To the Editor: In the article by Généreux et al. (Jan. 16 issue), 1 early transcatheter aortic-valve replacement (TAVR) was reported to be superior to clinical surveillance in reducing the incidence of a composite of death, stroke, or unplanned hospitalization for cardiovascular causes among patients with asymptomatic severe aortic stenosis. This trial is further expanding the therapeutic role of TAVR beyond the operative-risk classification. According to the Supplementary Appendix to the article, asymptomatic patients were defined as those having a negative treadmill stress test for any of the following: syncopal or presyncopal episode, angina, limiting dyspnea, drop in systolic blood pressure, . . .
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A 2025 study conducted a letter in Asymptomatic severe aortic stenosis. Early transcatheter aortic-valve replacement (TAVR) vs. Clinical surveillance was evaluated on Composite of death, stroke, or unplanned hospitalization for cardiovascular causes. Early transcatheter aortic-valve replacement (TAVR) was reported to be superior to clinical surveillance in reducing death, stroke, or unplanned cardiovascular hospitalization.
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