Key result
Calcified bicuspid aortic valve causes stroke via calcific embolus to the middle cerebral artery.
Why the study?
Calcific embolus is an uncommon complication of calcific aortic stenosis causing stroke, requiring detailed clinical characterization.
Case Report (n=1)
This case highlights calcific cerebral embolus as a rare but severe complication of calcific aortic stenosis in a patient with a bicuspid aortic valve.
May prompt vigilance for calcific emboli in bicuspid aortic valve stroke; leaves open optimal prevention strategies.
Calcific embolus (CE) is an uncommon complication of calcific aortic stenosis (CAS). We report a man who developed a stroke due to CE from CAS. A 40-year-old right-handed man had sudden onset of left-sided weakness, slurred speech, and bifrontal headache. He smoked two packs of cigarettes per day for many years and had a history of calcified bicuspid aortic valve. On neurologic examination, there was slurred speech, left inferior quandrantanopsia, and left hemiplegia. Cranial CT and MRI showed a right fronto-temporo-parietal infarct. On CT (Figure 1a) there was a high-density lesion consistent with calcium that appeared to be resting in the middle cerebral artery. The MRA showed diminished flow in the middle cerebral artery in the M1 segment at the level of the trifurcation (Figure 1b). This area corresponded to that of the calcific density on the …
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Shanmugam et al. (1997) conducted a case report in Calcific embolus from calcific aortic stenosis (n=1). Calcific embolus was evaluated on Stroke. A 40-year-old man with a calcified bicuspid aortic valve developed a stroke due to a calcific embolus resting in the middle cerebral artery.
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