Key result
A nuclease-resistant derivative of Poly(I)·Poly(C) was evaluated as a treatment for intranasal Japanese Encephalitis Virus infection in monkeys.
Why the study?
Does a nuclease-resistant derivative of Poly(I)·Poly(C) improve clinical response in monkeys infected intranasally with Japanese Encephalitis Virus?
Does a nuclease-resistant derivative of Poly(I)·Poly(C) improve clinical response in monkeys infected intranasally with Japanese Encephalitis Virus?
Poly(ICLC) partially protected JEV-challenged monkeys; leaves open whether interferon inducers warrant human trials.
"Intranasal Infection of Monkeys with Japanese Encephalitis Virus: Clinical Response and Treatment with a Nuclease-Resistant Derivative of Poly(I)·Poly(C)" published on Nov 1977 by The American Society of Tropical Medicine and Hygiene.
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Harrington et al. (1977) studied this question. A nuclease-resistant derivative of Poly(I)·Poly(C) was evaluated as a treatment for intranasal Japanese Encephalitis Virus infection in monkeys.
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