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Two trials were conducted to assess the effects of CGA-72662 (Larvadex®) on White Leghorns when fed continuously through the growing period. Trial 1 was a dosimetry battery trial to 4 weeks of age and Trial 2 was conducted in floor pens through 16 weeks and in cages from 17 to 32 weeks of age. CGA-72662 was fed from hatch to 4 weeks and from hatch to 20 weeks in Trials 1 and 2, respectively. CGA-72662 significantly depressed body weight of White Leghorn females when fed at levels greater than 250 ppm from hatch through either 4 or 20 weeks of age. Livability was not affected. Feed consumption was decreased by 1,000 ppm through 16 weeks of age (Trial 2). Egg production and feed conversion were not significantly affected by treatment. Internal and external egg quality were not affected consistently. It was concluded that CGA-72662 has no detrimental effects on growth, livability, or reproduction when fed at up to 250 ppm continuously during rearing.
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Brake et al. (1985) studied this question.
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