Off and on: A nickel-catalyzed benzannulation of alkynylboronates provides functionalized phenols with high levels of chemo- and regioselectively. While transmetalation of organoboron intermediate to organonickel does not occur during cycloaddition, it is “switched on” by addition of base, thus allowing a one-pot benzannulation and cross-coupling to be realized (see scheme; Pin=pinacolato, Ms=mesyl).
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Auvinet et al. (2011) studied this question.
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