Key result
Norovirus infection was associated with encephalitis in a 2-year-old girl, confirmed by detecting and genetically matching the viral genome in cerebrospinal fluid and stool.
This case report provides rare evidence of norovirus-associated encephalitis with genetically matched viral genomes in both stool and cerebrospinal fluid.
May warrant norovirus testing in unexplained pediatric encephalitis; leaves open causality and incidence for prospective studies.
We describe the case of 2-year-old girl with encephalitis associated with norovirus infection. The viral genome was detected in cerebrospinal fluid and stool by reverse transcription polymerase chain reaction. This is the first time in Spain and the second worldwide that the genome of norovirus from the stool sample and 2 cerebrospinal fluid samples were genetically characterized and matched.
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Sánchez-Fauquier et al. (2014) studied this question. Norovirus infection was associated with encephalitis in a 2-year-old girl, confirmed by detecting and genetically matching the viral genome in cerebrospinal fluid and stool.
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