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March 1, 2011Journal of Fish Biology

Myeloid differentiation factor 88 gene is involved in antiviral immunity in grass carp Ctenopharyngodon idella

Jianguo Su Jie Dong Teng Huang R. Zhang Can Yang Jianfu Heng

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Abstract

A full-length MyD88 cDNA (CiMyD88) was cloned and characterized from grass carp Ctenopharyngodon idella. CiMyD88 was found to be broadly expressed and was up-regulated by grass carp reovirus (GCRV) and CiMyD88 transcripts in vitro were rapidly elevated in C. idella kidney (CIK) cells after challenge with poly(I:C). These results suggest that CiMyD88 may be involved in the antiviral immune defence in C. idella.

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synapsesocial.com/papers/6ab5f23c4e7755fbe84c4877 https://doi.org/10.1111/j.1095-8649.2011.02910.x

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