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The anti-tumour effects of the sesquiterpene lactone, parthenin was studied both in vivo and in vitro . Parthenin showed marked cytotoxic activity to P815 mastocytoma, L1210 leukemia, and M-1 rhabdomyosarcoma cells in vitro. In vivo studies showed intraperitoneal drug administration could either cure mice or increase their survival time after intraperitoneal of subcutaneous injection with tumour cells. Key Word Index Parthenium hysterophorus - Asteraceae (Compositae) - Parthenin - Anti-tumour effect
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Mew et al. (1982) studied this question.
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