Key result
A 67-year-old man with known angioneurotic edema of the eyelids developed an angiosarcoma of the face, suggesting chronic edema may be a predisposing factor.
Case Report (n=1)
No
This case report describes a 67-year-old man who developed angiosarcoma of the face following chronic angioneurotic edema of the eyelids.
Alerts clinicians to possible angiosarcoma risk with chronic facial edema; leaves open causality in this Level 5 case.
Angiosarcomas of the head and neck region are both uncommon and highly invasive malignant tumors, and it has been speculated that chronic edema may be a predisposing factor. A case of known angioneurotic edema of the eyelids that became an angiosarcoma is reported herein. Report of a Case A 67-year-old man was seen at the Royal Marsden Hospital, London, in 1978 with a two-month history of a hardness of his eyelids and nodules on the left side of his face (Fig 1). The patient was a retired engineer and a native of the United States who had retired to the Caribbean island of Saint Lucia. The patient had enjoyed general good health, but five years earlier, mild diabetes had been diagnosed. He also had had bilateral cateract extraction at that time. The patient first noticed a problem with his eyes 30 years earlier, when he awoke one morning and noticed
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I. J. Mackenzie (1985) conducted a case report in Angiosarcoma of the face (n=1). Chronic edema was evaluated on Development of angiosarcoma. A 67-year-old man with known angioneurotic edema of the eyelids developed an angiosarcoma of the face, suggesting chronic edema may be a predisposing factor.
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