Symptom Profiles and Progression in Hospitalized and Nonhospitalized Patients with Coronavirus Disease, Colorado, USA, 2020

evere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease (COVID-19), was first detected in China in December 2019 (1,2).Within 1 month, COVID-19 cases were reported in numerous countries, including the United States (3).By the end of January 2020, the World Health Organization (WHO) declared the CO-VID-19 outbreak a public health emergency of international concern (4).After WHO's declaration, rapid acceleration of virus transmission in many parts of the world led WHO to characterize COVID-19 as a global pandemic in March (5).As of December 4, the United States had reported >14 million COVID-19 cases and ≈275,000 associated deaths (6).The large number of cases and deaths has created an unprecedented burden on the nation's healthcare system, necessitating triage of patients and the prioritization of testing.Initially, the most common symptoms of COV-ID-19 were reported to be fever, cough, and dyspnea (7-9).However, asymptomatic infections and additional symptoms common to other viral respiratory illnesses have been reported, including chills, fatigue, myalgia, sore throat, nasal congestion, rhinorrhea, nausea, vomiting, and diarrhea (10).Persons with COVID-19 have also reported anosmia (loss of smell) and ageusia (loss of taste) more frequently than with other viral respiratory diseases (11).Although ≈80% of persons with COVID-19 experience mild disease (12), to date most published reports of COVID-19 symptoms are derived from case-series and cross-sectional analyses of medical record reviews, primarily among hospitalized patients.Literature regarding symptoms experienced by nonhospitalized COVID-19 patients is growing, but information summarizing symptom duration, Symptom Profiles and Progression in Hospitalized and Nonhospitalized Patientswith Coronavirus Disease, Colorado, USA, 2020