Take a spin: The nucleoside Ç (C-spin), which contains a rigid nitroxide spin label, allows the structure and dynamics of nucleic acids into which it is incorporated to be studied by EPR spectroscopy (left spectrum). Reduction of the nitroxide with a mild reducing agent renders the nucleoside fluorescent (right spectrum). Thus, the same nucleic acid can be studied with two complementary spectroscopic techniques.
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Barhate et al. (2007) studied this question.
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