Paper-based microfluidic devices (μPAD) are a burgeoning platform of microfluidic analysis technology. The method described herein is for use in undergraduate and high school chemistry laboratories. A simple and convenient μPAD was fabricated by easy patterning of filter paper using a permanent marker pen. The usefulness of the device was demonstrated by determination of nitrite ion concentration employing a colorimetric assay. The results for real sample detection using this μPAD were satisfactory and show promise for use in other applications.
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Wang et al. (2015) studied this question.
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