Improvement of accommodation with anti-oxidant supplementation in visual display terminal users

OBJECTIVE: To determine the antioxidant supplementation effect on accommodation among VDT users. DESIGN: A double blind randomized placebo controlled study. Registered under ClinicalTrials.gov Identifier No. NCT00877201. PARTICIPANTS AND CONTROLS: Fourty right eyes of 40 healthy VDT users (30 females, 10 males, mean age: 43.8±2.8 years, range: 40-49 years). 20 subjects (15 females, 5 males; mean age: 44.0±2.7 years, range: 40-49 years). METHODS: Subjects were required to take an antioxidant supplement, 20 age and sex matched subjects (15 females, 5 males; mean age: 43.6±3.1 years, range: 40-49 years) were required to take placebo medication for 4 weeks. RESULTS: The mean of the change in accommodation power was significantly higher in the group receiving antioxidant supplements (0.20±0.50 Diopter(D)) compared to the placebo group (-0.12±0.48(D)) (p<0.05). CONCLUSIONS: Antioxidant supplementation was observed to improve accommodation in Japanese Visual Display Terminal (VDT) Users.