Psoriasis is a most perplexing disease that continues to afflict approximately 50 million people worldwide. Although many theories have been proposed for the cause of psoriasis, the primary cause of this hyperpro-liferative cutaneous disorder is unknown. Most treatments for psoriasis are associated with toxic side effects and there continues to be a need for a safe and effective method for treating this disfiguring disorder (27).
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Michael F. Holick (1989) studied this question.