Under oxidative stress: The oxidation of guanine and 8-oxo-7,8-dihydroguanine has been monitored by 18O-labeling methods. The combination of nucleobase radicals 1 with the carbonate radical anion 2 results in the net transfer of O− from CO3.− to the end products (see scheme).
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Crean et al. (2005) studied this question.
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