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January 18, 2010XenobioticaOpen Access

Identification of polymorphisms in the 3′-untranslated region of the human pregnane X receptor (PXR) gene associated with variability in cytochrome P450 3A (CYP3A) metabolism

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Authors

LOLauren OlesonTufts UniversityLMLisa L. von MoltkeAlkermes (United States)
David J. Greenblatt
David J. GreenblattBoston University

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Oleson et al. (2010) studied this question.

synapsesocial.com/papers/6ab60c8ea698145f830e4615https://doi.org/10.3109/00498250903420243
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Also Consider

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  1. 1Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method.2000 · 397 citations
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  3. 3Genetic Variants of PXR (NR1I2) and CAR (NR1I3) and Their Implications in Drug Metabolism and Pharmacogenetics2005 · 126 citations