Effect of platelet rich fibrin barier and bioceramic sealer in endodontic treatment immature teeth with periapical lesions

To evaluate the clinical and radiographic outcomes of endodontic treatment using PRF apical barrier and bioceramic sealer for immature teeth with periapical lesions after 1, 2, 3, 6 months. In this prospective case series, the platelet-rich fibrin (PRF) membrane was used as an apical barrier combined with a bioceramic sealer and gutta percha cone in root canal obturation for 15 permanent teeth with open apex and periapical lesion in 14 patients in the National Hospital of Odonto-Stomatology HoChiMinh city (10 teeth in male and 5 teeth in female, with patients aged from 7 to 14 years). Data on clinical symptoms and radiograph variables were collected before and after treatment 1, 2, 3 and 6 months. All 15 cases had successful clinical outcome, with no clinical symptoms after treatment. During the follow-up period, the dimensions of periapical lesions decreased gradually and significantly. At the 6-month re-examination, no residual periapical radiolucency was detectable on the radiographs . Favorable clinical and radiographic outcomes were observed in this propective cases series using MTA Bio-C ® Sealer in combination with platelet-rich fibrin (PRF) as an apical barrier in the treatment of immature permanent teeth with periapical lesions.