Key result
UACR and UPCR predict kidney failure, disease progression, and cardiovascular outcomes in CKD.
Why the study?
Does prediction using urinary albumin-creatinine ratio (UACR) improve prediction of kidney failure, CKD progression, and cardiovascular outcomes compared to urinary protein-creatinine ratio (UPCR) in an established CKD cohort?
Does prediction using urinary albumin-creatinine ratio (UACR) improve prediction of kidney failure, CKD progression, and cardiovascular outcomes compared to urinary protein-creatinine ratio (UPCR) in an established CKD cohort?
UACR and UPCR should not yet alter CKD risk stratification; leaves open which ratio offers superior outcome prediction.
This study compares the clinical utility of the urinary albumin-creatinine ratio (UACR) vs the the urinary protein-creatinine ratio (UPCR) for prediction of kidney failure, chronic kidney disease (CKD) progression, and cardiovascular outcomes in an established CKD cohort.
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Verma et al. (2026) studied this question. Urinary albumin-creatinine and protein-creatinine ratios were evaluated for predicting kidney failure, disease progression, and cardiovascular outcomes in a chronic kidney disease cohort.
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