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Aspergillus quadrilineatus , isolated from the Nigerian cereal "acha", demonstrated antibiotic activity in both static and submerged cultures of a variety of fungal and bacterial species of clinical importance. The time-course for the induction of antibiotic activity was determined, as well as the effects of different carbon sources, pH, temperature and bivalent cations.
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Irobi et al. (2000) studied this question.
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