Current clinical uses of intravenous immunoglobulin

Current clinical uses of intravenous immunoglobulin Intravenous immunoglobulin (IVIG) therapy can be used to supplement low IgG levels (replacement therapy) or to modulate the immune system (high-dose therapy) IVIG operates by a range of mechanisms depending on the condition being treated IVIG products are different from one another and not interchangeableThere is good evidence of efficacy for IVIG in many conditions, including antibody deficiency syndromes, autoimmune neuropathies, Kawasaki disease, idiopathic thrombocytopenic purpura and some vasculitides Careful patient selection is essential, given the world shortage of IVIG, the cost and time needed to administer it