Rapid Clearance of Necrolytic Migratory Erythema Following Intravenous Administration of Amino Acids

to improve in the next days (Figure 2).Two weeks after amino acid treatment, radiolabeled somatostatin analogue therapy was given to induce tumor reduction and allow for tumor resection without affecting the adjacent blood vessels.Discussion | The diagnosis of NME is often challenging, both clinically and histologically.The skin lesions can mimic other dermatoses, and histologic analysis is considered a poor diagnostic tool, 3 as was evident in the present case.Delay in diagnosis is also attributed to the rarity of the tumor, underrecognition of the dermatologic presentation, and the lack of specificity of the other symptoms.4 Therefore, a high index of suspicion should be maintained when a patient presents with suggestive skin and systemic symptoms.Necrolytic migratory erythema significantly affects patient quality of life and is resistant to treatment.The use of intravenous amino acids as a treatment for NME has been reported, 5 but the quick resolution of the skin lesions was not well documented.We showed the quick resolution of the skin and mucosal lesions after only 24 hours, leading to marked improvement in quality of life for the patient.