Synthesis, spectral and antimicrobial studies of chloroantimony(III)di[3(2′-hydroxyphenyl)-5-(4-substitutedphenyl)pyrazolinates]

Dichloroantimony(III) pyrazolinates and chloroantimony(III) dipyrazolinates of the type SbCl2(C15H12N2OX) and SbCl(C15H12N2OX)2 [where C15H12N2OX = 3(2′-hydroxyphenyl)-5-(4-X-phenyl)pyrazoline, X=H in1 and5;–CH3 in2 and6;–OCH3 in3 and7 and–Cl in4 and8] have been synthesized by reaction of SbCl3 and sodium salt of pyrazolines in 1 : 1 and 1 : 2 molar ratio in anhydrous benzene at elevated temperature. These newly synthesized derivatives have been characterized by elemental analysis (C, H, N, Cl and Sb), molecular weight measurement and spectral studies [IR and1H and13C NMR]. The free pyrazoline and some dichloroantimony(III) pyrazolinates and chloroantimony(III) dipyrazolinates have been screened for antibacterial and antifungal activities, with some dichloroantimony(III) pyrazolinates and chloroantimony(III) dipyrazolinates exhibiting higher antibacterial and antifungal effects than free pyrazoline and some antibiotics.