Mesotherapy using Vitamin C as an anti-inflammatory agent in persistent gingival inflammation: A case series

BACKGROUND: Mesotherapy is a minimally invasive procedure which involves local intradermal therapy (LIT) with biologically active substances given in minor quantities to the area of pathology. Vitamin C is an important antioxidant agent which can modulate the attenuation of inflammatory process and enhance tissue repair. AIM: The aim of this study was to investigate the efficacy of local injections of Vitamin C for treating persisting inflammation of the gingiva. MATERIALS AND METHODS: After phase I therapy was completed, five patients with persisting chronic inflammation of the gingiva were injected with the same dosages of Vitamin C into the gingival tissues. Patients were evaluated each week for resolution of gingival inflammation. RESULTS: Clinical observation showed a significant improvement in inflammation of the injected sites during recall appointments. CONCLUSIONS: LIT with Vitamin C has a synergistic interaction along with scaling and root planing in the treatment of persistent gingival inflammation.