Three crude extracts, including hexane, dichloromethane and methanolic extracts from Turraea heterophylla and Terminalia glaucescens used in Togo ethnomedicine to treat common infections, were screened in vitro for antimicrobial activity. Staphylococcus aureus , Bacillus subtilis , Escherichia coli, Salmonella typhimurium, Mucor sp., Rhisopus stolonifer, Trichoderma viride, Microsporum ferrugineum and Candida albicans have been used as test organisms. The dichloromethane extract of Turraea heterophylla roots was the most active with a minimum inhibitory concentration (MIC) between 12.5mg/ml and 50mg/ml. The inhibition percentage is above 98% for bacterial strains and 70% for dermatophytes. The methanolic extract of stem bark, stem and roots of Terminalia glaucescens showed antimicrobial activity with a minimum inhibitory concentration (MIC) between 6,25mg/ml and 12,5mg/ml and the inhibition percentage above 99,95% for bacterial strains. The preliminary phytochemical screening revealed the presence of tannins, alkaloids, flavonoids and saponosides. Acknowledgement : The Rwandese Government and the Ministry of Education are gratefully acknowledged for the grant to Ingabire Goretti
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Ingabire et al. (2007) studied this question.