Key result
This article summarizes updates from 5 ongoing clinical studies investigating neurodevelopmental outcomes after exposure to anesthetic drugs in infants and children.
Why the study?
Do anesthetic drugs affect neurodevelopmental outcomes in infants and children?
Do anesthetic drugs affect neurodevelopmental outcomes in infants and children?
This review summarizes ongoing clinical studies investigating the potential neurodevelopmental toxicity of anesthetic drugs in pediatric populations.
During the Fifth Pediatric Anesthesia Neurodevelopmental Assessment Symposium, experts and stakeholders met to present and discuss recent advances made in the study of neurodevelopmental outcomes after exposure to anesthetic drugs in infants and children. This article summarizes the update of 5 ongoing clinical studies: General Anesthesia compared to Spinal Anesthesia, Toxicity of Remifentanil and Dexmedetomidine, Mayo Anesthesia Safety in Kids, the University of California San Francisco human cohort study, and Columbia University Medical Center Neonatal Magnetic Resonance Imaging study. The purpose of this summary is to discuss the contributions and limitations of these studies, how they fit into the published literature, and what questions remain to be answered.
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Pinyavat et al. (2016) conducted a review in Neurodevelopmental outcomes after exposure to anesthetic drugs. Anesthetic drugs was evaluated on Neurodevelopmental outcomes. This article summarizes updates from 5 ongoing clinical studies investigating neurodevelopmental outcomes after exposure to anesthetic drugs in infants and children.
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