No correlation of intensity of phlebotomy regimen with risk of thrombosis in polycythemia vera: evidence from European Collaboration on Low-Dose Aspirin in Polycythemia Vera and Cytoreductive Therapy in Polycythemia Vera clinical trials

our results indicate that the frequency of phlebotomies in PV patients on HU does not represent a risk factor for future thrombosis in PV patients and do not support the need to shift from HU plus TP to second line drugs, and indirectly reinforce that a low HCT is the key variable to reduce the thrombotic risk in PV patients