Subcutaneous Panniculitis-Like T Cell Lymphoma Demonstrated on Gallium-67 Scintigraphy

A 52-year-old obese, diabetic man presented with fever, night sweats, a 20-kg weight loss, and subcutaneous masses on the legs, arms, and abdominal wall. Whole-body gallium-67 scintigraphy was performed to investigate pyrexia of unknown origin and demonstrated gallium avidity in the subcutaneous masses. Subsequent core biopsy of a skin lesion demonstrated subcutaneous panniculitis-like T cell lymphoma (SPTCL). The patient underwent combination chemotherapy and responded clinically with resolution of his systemic symptoms, healing of the subcutaneous masses, and complete resolution of the previously demonstrated gallium-avid skin lesions. Gallium scintigraphy should be considered in cases of possible lymphomatous infiltration of the skin.