The anti-acetylcholinesterase activities of the alkaloids of Physostigma venenosum seeds

This is the authors' abstract. We don't add key points for this paper.

Anti-acetylcholinesterase activities of physostigmine, physovenine, Na-norphysostigmine, geneserine and eseramine have been investigated in vitro using erythrocyte acetylcholinesterase. The former three bases show comparable activities whereas geneserine and eseramine are inactive under the same experimental conditions. The biologically active form of these bases is discussed in light of these enzyme inhibitory studies.