Key result
Acupuncture modulates multiple components of the neurovascular unit in ischemic stroke.
Why the study?
The neurovascular unit mechanism of ischemic stroke and the multi-target effects of acupuncture on this unit have been increasingly recognized but require comprehensive review.
Does acupuncture regulate the neurovascular unit in ischemic stroke?
Does acupuncture regulate the neurovascular unit in ischemic stroke?
Acupuncture may exert its therapeutic effects in ischemic stroke through multi-target regulation of the neurovascular unit.
Answers are grounded in this paper and cite their sources.
May support multi-target neurovascular regulation by acupuncture in ischemic stroke; hypothesis-generating and requires prospective RCTs.
Ischemic stroke is a type of clinical syndrome caused by brain blood supply disorders due to various cerebrovascular diseases, which lead to local cerebral ischemia, hypoxic necrosis, and corresponding neurological defects. In recent years, the neurovascular unit mechanism of ischemic stroke has been proposed in modern medicine. With the principles of syndrome differentiation-based treatment and holistic view in traditional Chinese medicine, acupuncture has the advantage of multi-target and multi-link effect and good clinical efficacy on this disease, and current studies have shown that acupuncture has a marked effect on each component and the whole of neurovascular unit. This article reviews the effect of acupuncture on the regulation of blood-brain barrier, astrocytes, microglial cells, neurons, and neurovascular units.
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Li et al. (2019) conducted a review in Ischemic stroke. Acupuncture was evaluated on Regulation of blood-brain barrier, astrocytes, microglial cells, neurons, and neurovascular units. Acupuncture has a marked effect on each component and the whole of the neurovascular unit in the treatment of ischemic stroke.
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