Answers are grounded in this paper and cite their sources.
Indoles and azaindoles undergo smooth oxidation with 2-iodoxybenzoic acid (IBX) in the presence of indium(III) chloride at 80 °C to afford the corresponding isatins in excellent yields. This method is very useful for the direct preparation of isatins from indoles. The reaction proceeds smoothly in aqueous media and the products are obtained in excellent yields.
No takes yet. Share an insight, caveat, or question.
Yadav et al. (2007) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: