Underwater endoscopic mucosal resection for gastric neoplasms

Underwater endoscopic mucosal resection (UEMR) is widely used to treat colonic lesions. However, reports of its application for gastric lesions are scarce. This study aimed to evaluate the efficacy and safety of UEMR for gastric lesions (G-UEMR). In this retrospective study, patients with definite or suspicious gastric neoplasms who underwent G-UEMR between January 2014 and June 2021 were identified in the databases of two tertiary hospitals. Procedure time, R0 resection rate, (AE) rates were assessed. The 32 lesions (32 patients) included 15 adenocarcinomas, seven adenomas, five hyperplastic polyps, and two submucosal lesions. Of them, three were non-neoplastic mucosa despite suspicion of neoplasm on prior endoscopy. The median lesion size was 10 mm (range 2–50 mm). The median procedure time was 4 minutes (range 1–20 minutes). R0 resections were achieved in all (n = 15 [100 %]) early gastric cancer patients. There were no immediate AEs except one case of aspiration pneumonia. G-UEMR appears to be a safe, easy, and effective method for removing small gastric lesions. Publication History Received: 08 February 2022 Accepted after revision: 12 May 2022 Article published online: 15 August 2022 © 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/) Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany