Key result
Inadequate glucose control in patients with type 2 diabetes was associated with significantly lower FEV1 (mean difference -75.4 mL) and FVC compared to those with adequate control.
Why the study?
Is inadequate glucose control associated with impaired lung function and systemic inflammation in patients with type 2 diabetes?
Population
495 patients with type 2 diabetes from the Colombian Diabetes Association Center in Bogotá.
Comparison
Inadequate glucose control (HbA1c > 7%) vs Adequate glucose control (HbA1c ≤ 7%)
Design
Cross-sectional
Authors
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May warrant lung function monitoring in poorly controlled T2D; leaves open whether glycemic improvement affects spirometry.
Cross-Sectional (n=495)
No
Is inadequate glucose control associated with impaired lung function and systemic inflammation in patients with type 2 diabetes?
Mean Difference: -75.4 (95% CI -92.2–-58.6)
Absolute Event Rate: -164.9% vs -89.5%
p-value: p=<0.0001
Inadequate glucose control in type 2 diabetes is associated with significantly worse pulmonary function and increased systemic inflammation.
Dennis et al. (2010) conducted a cross-sectional in Type 2 diabetes (n=495). Inadequate glucose control (HbA1c > 7%) vs. Adequate glucose control (HbA1c ≤ 7%) was evaluated on Mean residual value for forced expiratory volume (FEV1) (MD -75.4 mL, 95% CI -92.2 to -58.6, p=<0.0001). Inadequate glucose control in patients with type 2 diabetes was associated with significantly lower FEV1 (mean difference -75.4 mL) and FVC compared to those with adequate control.
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