Key result
Total knee arthroplasty performed without a tourniquet did not significantly improve active knee flexion at day 3 compared to surgery with a tourniquet (mean difference 3.2°).
Why the study?
Does total knee arthroplasty without a tourniquet improve rehabilitation-related results compared to using a tourniquet in patients with knee osteoarthritis?
RCT (n=88)
Double-blind
1:1 in blocks of 2, stratified by surgeon
No
Does total knee arthroplasty without a tourniquet improve rehabilitation-related results compared to using a tourniquet in patients with knee osteoarthritis?
Performing total knee arthroplasty without a tourniquet does not provide a clear clinically relevant benefit for rehabilitation compared to using a tourniquet.
PURPOSE: When a tourniquet is used during surgery on the extremities, the pressure applied to the muscles, nerves and blood vessels can cause neuromuscular damage that contributes to postoperative weakness. The hypothesis was that the rehabilitation-related results would be improved if total knee arthroplasty (TKA) is performed without the use of a tourniquet. METHODS: 81 patients with osteoarthritis of the knee who underwent TKA surgery were randomized to surgery with or without tourniquet. Active flexion and extension of the knee, pain by visual analog scale (VAS), swelling by knee circumference, quadriceps function by straight leg raise, and timed up and go (TUG) test results were measured before and up to 3 months after surgery. RESULTS: ANCOVA revealed no between-groups effect for flexion of the knee at day 3 postsurgery. Compared with the tourniquet group, the nontourniquet group experienced elevated pain at 24 h, with a mean difference of 16.6 mm, p = 0.005. The effect on mobility (TUG test) at 3 months was better in the nontourniquet group, with a mean difference of -1.1 s, p = 0.029. CONCLUSIONS: The hypothesis that the rehabilitation-related results would be improved without a tourniquet is not supported by the results. When the results in this study for surgery performed with and without tourniquet are compared, no clear benefit for either procedure was observed, as the more pain exhibited by the nontourniquet group was only evident for a short period and the improved mobility in this group was not at a clinically relevant level. LEVEL OF EVIDENCE: Inconsistent results, Level II.
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Alexandersson et al. (2018) conducted an RCT in Primary osteoarthritis of the knee (n=88). Total knee arthroplasty without tourniquet vs. Total knee arthroplasty with tourniquet was evaluated on Active flexion of the knee at day 3 (MD 3.2, 95% CI -1.0 to 7.4, p=n.s.). Total knee arthroplasty performed without a tourniquet did not significantly improve active knee flexion at day 3 compared to surgery with a tourniquet (mean difference 3.2°).
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