One-Pot Oxidation and Wittig Olefination of Alcohols Using O-Iodoxybenzoic Acid and Stable Wittig Ylide*

Benylic, allylic, and propargylic alcohols, as well as diols, can be oxidized with o-iodoxybenzoic acid (IBX) in the presence of stabilized Wittig ylide[1] Maryanoff, B. E. and Reitz, A. B. 1989. Chem. Rev., : 863[Crossref], [Web of Science ®] , [Google Scholar] to generate α,β-unsaturated ester in one pot. This is useful when the intermediate aldehydes are unstable and difficult to isolate.