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Oxidized cellulose (Surgicel) has been used as a haemostatic agent in neurosurgery for five decades. Complications have been few. Two cases are reported of granulomatous reaction to oxidised cellulose two months and twelve months after removal of intracranial meningiomas. Both appeared as contrast enhancing space occupying lesions on CT scan and were taken for recurrence of the tumour.
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Sandhu et al. (1996) studied this question.
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