The different functional complexes of ribosomes with elongation factor F (EF-G) were studied by digestion experiments with trypsin. It was found that upon interaction of EF-G with ribosomes the L7/L12 proteins are sensitive to trypsin and are trypsin resistant after dissociation of EF-G from ribosomes. The significance of conformational alterations in the L7/L12 and also in the other proteins in the translation process is discussed.
No takes yet. Share an insight, caveat, or question.
Gudkov et al. (1984) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: