Key result
CMR pulmonary artery distensibility index correlates with invasive stiffness and predicts functional class in PAH.
Why the study?
Pulmonary arterial hypertension is a fatal disease characterized by elevated pulmonary artery pressure and vascular remodeling leading to right heart failure and death.
The Pulmonary Artery Distensibility Index is proposed as a non-invasive marker for monitoring the progression of pulmonary arterial hypertension.
May support non-invasive PAH monitoring; hypothesis-generating and requires prospective validation before adoption.
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Yoshihiro Fukumoto (2011) conducted an editorial in Pulmonary Arterial Hypertension. Cardiac magnetic resonance (CMR)-derived pulmonary artery distensibility index was evaluated. CMR-derived pulmonary artery distensibility index correlates with invasively measured pulmonary artery stiffness and predicts functional class in patients with pulmonary arterial hypertension.
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