Letters3 April 2001Adherence to Protease InhibitorsDavid L. Paterson, MD and Nina Singh, MDDavid L. Paterson, MDVeterans Affairs Medical Center; Pittsburgh, PA 15240 (Paterson, Singh) and Nina Singh, MDVeterans Affairs Medical Center; Pittsburgh, PA 15240 (Paterson, Singh)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-134-7-200104030-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Murri and colleagues ask about the distribution of completely antiretroviral-naive patients. This information can be found in our Table 4—9% (2 of 23) of patients in our series who had adherence of 95% or more and 10% (6 of 58) of those with less than 95% adherence had never received any antiretroviral medication.It is widely agreed that virologic outcome depends both on adherence and other factors, such as viral resistance to antiretroviral medications. All five patients who had virologic failure despite at least 95% adherence had been heavily pretreated with antiretroviral medications. These five patients had been ... Author, Article, and Disclosure InformationAffiliations: Veterans Affairs Medical Center; Pittsburgh, PA 15240 (Paterson, Singh) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoAdherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection David L. Paterson , Susan Swindells , Jeffrey Mohr , Michelle Brester , Emanuel N. Vergis , Cheryl Squier , Marilyn M. Wagener , and Nina Singh Adherence to Protease Inhibitors Rita Murri , Adriana Ammassari , and Andrea Antinori Metrics Cited ByFacility-level intervention to improve attendance and adherence among patients on anti-retroviral treatment in Kenya—a quasi-experimental study using time series analysisCo-occurrence of Treatment Nonadherence and Continued HIV Transmission Risk Behaviors: Implications for Positive Prevention Interventions 3 April 2001Volume 134, Issue 7Page: 625KeywordsAntiretroviralsDrugsGenotypingHIVHIV-1Minimal essential mediumMutationProtease inhibitors ePublished: 3 April 2001 Issue Published: 3 April 2001 CopyrightCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
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Paterson et al. (2001) studied this question.